Buy Extra Super P Force Tablets Generic drug of Sildenafil/Dapoxetine online at a reasonable price from the most trusted website to cure Erectile Dysfunction.
What Is Extra Super P Force Tablets?
Extra Super P Force 200mg Tablets (Sildenafil Citrate 100mg & Dapoxetine 100mg) is a new form of hybrid combination treatment of ED and premature ejaculation (ejaculatio praecox).
Sildenafil is a Selective inhibitor cyclic guanosine monophosphate(cGMP) specific phosphodiesterase type-5 (PDE5).
Dapoxetine is a short-acting serotonin reuptake inhibitor (SSRI) develop specifically for the treatment of premature ejaculation. Each film coated tablets contain Sildenafil Citrate 100mg and Dapoxetine 100mg.
when is it prescribed?
Extra Super P Force is the treatment of male erectile dysfunction and premature ejaculation.
In Contraindication Contraindicated in patients with known hypersensitivity to any component of the tablets. Consistent with it knows the effect on the nitric oxide/cGMP pathway, Sildenafil was shown to potentiate the hypotensive effect of nitrates, and its administration to patients who are using organic nitrate, either regularly and intermittently, in any form is therefore contraindicated. Sildenafil is not specified for use in women and individuals below 18 years.
How does work?
Sildenafil: The physiologic mechanism action of the erection of the panis require the circulate of nitricoxide in the corpus cavernosum during sexual stimulation. Nitricoxide then activates the enzyme guanylate cyclase, Which results in increased level of cGMP (cyclic guanosine monophosphate), producing smooth muscle composure in the corpus cavernosum and permit inflow of blood, Sildenafil has no direct relaxant effect or isolated human corpus cavernosum,
However, enhances the effect of nitric oxide by inhibiting phosphodiesterase type-5 (PDE5), which is responsible for the degradation of cGMP in the corpus cavernosum. When sexual stimulation purpose local release of nitric oxide, inhibition of PDE5 by sildenafil causes increased level of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil at recommended doses does not affect in the absence of sexual stimulation.
Dapoxetine: Dapoxetine exhibits its efficacy by perimirilary inhibiting the reuptake of the serotonin transporter. It was also shown to bind and inhibit reuptake the transporters of dopamine and norepinephrine.