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What is HCG ZyhCG Injection?
This Injection is a lyophilized preparation of human Chorionic Gonadotropin (hCG) – a gonad-stimulating polypeptide hormone secreted by the human placenta and obtained from the urine of pregnant women. The action of this medication is virtually identical to that of pituitary LH although hCG appears to have a little degree of FSH activity as well. It stimulates the production of gonadal steroid hormones by stimulating the interstitial cells (Leydig cells) of the testes to produce androgen and the corpus luteum of the ovaries to produce progesterone.this medicine is the composition of Mannitol I.P, Disodium hydrogen orthophosphate I.P., Sodium Dihydrogen orthophosphate I.P.
How does work?
This medication must be administered parenterally since this injection is destroyed in the GI tract is a polypeptide. Following intramuscular injection, a detectable rise in serum hCG(Human Chorionic Gonadotropin) levels is seen in 2 hours; peak levels are reached in 6 hours and remain at this level for 36 hours. These injection levels begin to decline at the 48-hour approach baseline (undetectable) levels after 72 hours.
Following IM administration of this injection, this injection distributed mainly into the testes in males and the ovaries in females. Smaller amounts of the drug may be distributed into the proximal tubules of the renal cortex. Blood concentration of this injection decline in a biphasic manner.
The half-life in the initial phase is reported to be about 11, hours and in the terminal phase about 23 hours, About 10%-20% of a therapeutic dose of this injection is excreted in the urine within 24 hours, delectable amounts of the drug may be detected in the urine up to 3-4 days. For intramuscular and subcutaneous use only.